Originally posted by Pooka1
View Post
Announcement
Collapse
No announcement yet.
Advanced Maternal Age Associated with AIS?
Collapse
X
-
Last edited by Ballet Mom; 02-08-2011, 10:15 AM.
-
Originally posted by Ballet Mom View PostBut these familial cases may very well differ. They may be the most difficult cases to treat...as shown by the juvenile cases which also appear primarily in those families. And these familial cases are what Axial Biotech is researching.
1. ethnicity
2. fraction of male probands
3. age at first presentation
4. severity in affected individuals (P>0.1 in all instances).
That seems like they are all the same animal and the patterns of genetic inheritance (autosomal dominant and complex/polygeenic/multifactorial) blend into each other or completely overlap.
Gieven that 1/4 to 1/3 of the cases appear to be a straight autosomal dominant pattern, that appears to be the nail in the coffin on germ theory for them at least (or a perfectly ubiquitous germ in space and time, i.e. NOT a germ).Sharon, mother of identical twin girls with scoliosis
No island of sanity.
Question: What do you call alternative medicine that works?
Answer: Medicine
"We are all African."
Comment
-
B the way, where does it state Scoliscore was developed excusively among these autosomal dominant groups? Rorher said they didn't ask her about her family so they can't know if all the data or some of the data or none of the data are from this group or the larger apparently complex group. It probably reflects the prevalence in the larger population.Sharon, mother of identical twin girls with scoliosis
No island of sanity.
Question: What do you call alternative medicine that works?
Answer: Medicine
"We are all African."
Comment
-
Originally posted by Pooka1 View PostBut the article said they don't differ at least in terms of
1. ethnicity
2. fraction of male probands
3. age at first presentation
4. severity in affected individuals (P>0.1 in all instances).
That seems like they are all the same animal and the patterns of genetic inheritance (autosomal dominant and complex/polygeenic/multifactorial) blend into each other or completely overlap.
Gieven that 1/4 to 1/3 of the cases appear to be a straight autosomal dominant pattern, that appears to be the nail in the coffin on germ theory for them at least (or a perfectly ubiquitous germ in space and time, i.e. NOT a germ).
I could still see that "a germ" of some sort triggers the initial curvature. It's certainly not ruled out.
Comment
-
Originally posted by Ballet Mom View PostMy daughter responded nicely to bracing. Others don't. It could very well be the tenacity of progression that differs.
I could still see that "a germ" of some sort triggers the initial curvature. It's certainly not ruled out.
"the different curve types in RGs and BDs suggest that the exercise pattern over many years determines which type of scoliosis develops, although not the curve severity".
So in actuality, apparently different curve types are developing in response to whether one is in rhythmic gymnastics versus ballet. That is amazing.
Comment
-
Originally posted by Pooka1 View PostB the way, where does it state Scoliscore was developed excusively among these autosomal dominant groups? Rorher said they didn't ask her about her family so they can't know if all the data or some of the data or none of the data are from this group or the larger apparently complex group. It probably reflects the prevalence in the larger population.Last edited by Ballet Mom; 02-08-2011, 10:57 AM.
Comment
-
Originally posted by Ballet Mom View PostThat would reflect that the larger group of scoliosis has multifactorial scoliosis and not necessarily genetically driven other than having genetic predispositions to it. i.e. body type, hyperextended joints, etc.
Comment
-
Originally posted by hdugger View PostAccording to Scoliscore, it's *all* multifactorial. Either that or they simply don't talk about or test for the purely familial form.
The main issue with the test is this...if it's accurate and works, it's okay to use it. Unfortunately, it obviously doesn't work well enough. It lets kids progress to at least forty degrees and lets many of them progress to surgery anyway without treatment. As far as I'm concerned, it would be a travesty to use this test as the standard of care.
It's like doctors stating that the odds of that colon polyp changing into a cancerous tumor is low, and therefore we won't remove it. And if you're one of the unlucky ones that has a polyp that turns into colon cancer, well...we have surgery to fix it. I'm sure no one will mind having a colostomy. What a bizarre way to conduct medicine. As far as I'm concerned it's a "scientific" way to remove the cost of bracing and office visits from the medical system. And it's not right.
And did anyone notice that the inventors of the Scoliscore test have a vision with no place for bracing in the future? And much less treatment of all cases. How is that okay? Bracing has saved my daughter and I resent any scientist stating that others will not be able to receive that same treatment that worked perfectly well for her and avoided surgery.Last edited by Ballet Mom; 02-08-2011, 11:34 AM.
Comment
-
Originally posted by Ballet Mom View PostMy daughter responded nicely to bracing. Others don't. It could very well be the tenacity of progression that differs.
I could still see that "a germ" of some sort triggers the initial curvature. It's certainly not ruled out.Sharon, mother of identical twin girls with scoliosis
No island of sanity.
Question: What do you call alternative medicine that works?
Answer: Medicine
"We are all African."
Comment
-
Originally posted by Ballet Mom View PostThe blurb of the article I am able to access also says the following:
"the different curve types in RGs and BDs suggest that the exercise pattern over many years determines which type of scoliosis develops, although not the curve severity".
So in actuality, apparently different curve types are developing in response to whether one is in rhythmic gymnastics versus ballet. That is amazing.Sharon, mother of identical twin girls with scoliosis
No island of sanity.
Question: What do you call alternative medicine that works?
Answer: Medicine
"We are all African."
Comment
-
Originally posted by Ballet Mom View PostThe original genetic data was from the familial type of scoliosis.Sharon, mother of identical twin girls with scoliosis
No island of sanity.
Question: What do you call alternative medicine that works?
Answer: Medicine
"We are all African."
Comment
-
Originally posted by hdugger View PostAccording to Scoliscore, it's *all* multifactorial. Either that or they simply don't talk about or test for the purely familial form.Sharon, mother of identical twin girls with scoliosis
No island of sanity.
Question: What do you call alternative medicine that works?
Answer: Medicine
"We are all African."
Comment
-
Originally posted by Ballet Mom View PostWhat's not ubiquitous about chicken pox?Sharon, mother of identical twin girls with scoliosis
No island of sanity.
Question: What do you call alternative medicine that works?
Answer: Medicine
"We are all African."
Comment
Comment